Sample Course Curriculum

3D Printing for Medicine

(May 3, 2019)

1. Current advances and future perspectives of 3D printing natural-derived biopolymers.

Liu J, Sun L, Xu W, Wang Q, Yu S, Sun J. Carbohydr Polym. 2019 Mar 1;207:297-316. doi: 10.1016/j.carbpol.2018.11.077.


2. Tissue Engineering and 3-Dimensional Modeling for Facial Reconstruction.

VanKoevering KK, Zopf DA, Hollister SJ. Facial Plast Surg Clin North Am. 2019 Feb;27(1):151-161. doi: 10.1016/j.fsc.2018.08.012.


3. In vitro human tissues via multi-material 3-D bioprinting.

Kolesky DB, Homan KA, Skylar-Scott M, Lewis JA. Altern Lab Anim. 2018 Sep;46(4):209-215.


4. The clinical use of 3D printing in surgery.

Pugliese L, Marconi S, Negrello E, Mauri V, Peri A, Gallo V, Auricchio F, Pietrabissa A. Updates Surg. 2018 Sep;70(3):381-388. doi: 10.1007/s13304-018-0586-5.


5. 3D printing for preoperative planning and surgical training: a review.

Ganguli A, Pagan-Diaz GJ, Grant L, Cvetkovic C, Bramlet M, Vozenilek J, Kesavadas T, Bashir R. Biomed Microdevices. 2018 Aug 4;20(3):65. doi: 10.1007/s10544-018-0301-9.


6. Review fantastic medical implications of 3D-printing in liver surgeries, liver regeneration, liver transplantation and drug hepatotoxicity testing: A review.

Wang JZ, Xiong NY, Zhao LZ, Hu JT, Kong DC, Yuan JY. Int J Surg. 2018 Aug;56:1-6. doi: 10.1016/j.ijsu.2018.06.004.


7. Three-dimensional bioprinting of stem-cell derived tissues for human regenerative medicine.

Skeldon G, Lucendo-Villarin B, Shu W. Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750). pii: 20170224. doi: 10.1098/rstb.2017.0224.


8. 3D printing from microfocus computed tomography (micro-CT) in human specimens: education and future implications.

Shelmerdine SC, Simcock IC, Hutchinson JC, Aughwane R, Melbourne A, Nikitichev DI, Ong JL, Borghi A, Cole G, Kingham E, Calder AD, Capelli C, Akhtar A, Cook AC, Schievano S, David A, Ourselin S, Sebire NJ, Arthurs OJ. Br J Radiol. 2018 Jul;91(1088):20180306. doi: 10.1259/bjr.20180306.


9. 3D Bioprinting of Artificial Tissues: Construction of Biomimetic Microstructures.

Luo Y, Lin X, Huang P. Macromol Biosci. 2018 Jun;18(6):e1800034. doi: 10.1002/mabi.201800034.


10. 3D bio-printing technology for body tissues and organs regeneration.

Biazar E, Najafi S M, Heidari K S, Yazdankhah M, Rafiei A, Biazar D. J Med Eng Technol. 2018 Apr;42(3):187-202. doi: 10.1080/03091902.2018.1457094.


11. The Evolution of Polystyrene as a Cell Culture Material.

Lerman MJ, Lembong J, Muramoto S, Gillen G, Fisher JP. Tissue Eng Part B Rev. 2018 Oct;24(5):359-372. doi: 10.1089/ten.TEB.2018.0056.


12. 3D printing processes for photocurable polymeric materials: technologies, materials, and future trends.

Taormina G, Sciancalepore C, Messori M, Bondioli F. J Appl Biomater Funct Mater. 2018 Jul;16(3):151-160. doi: 10.1177/2280800018764770.


13. 3D Printed Organ Models for Surgical Applications.

Qiu K, Haghiashtiani G, McAlpine MC.

Annu Rev Anal Chem (Palo Alto Calif). 2018 Jun 12;11(1):287-306. doi: 10.1146/annurev-anchem-061417-125935.


14. Tissue and Organ 3D Bioprinting.

Xia Z, Jin S, Ye K. SLAS Technol. 2018 Aug;23(4):301-314. doi: 10.1177/2472630318760515.


15. Enabling personalized implant and controllable biosystem development through 3D printing.

Nagarajan N, Dupret-Bories A, Karabulut E, Zorlutuna P, Vrana NE. Biotechnol Adv. 2018 Mar - Apr;36(2):521-533. doi: 10.1016/j.biotechadv.2018.02.004.


16. 3D printing applications for transdermal drug delivery.

Economidou SN, Lamprou DA, Douroumis D. Int J Pharm. 2018 Jun 15;544(2):415-424. doi: 10.1016/j.ijpharm.2018.01.031.


17. Clinical efficacy and effectiveness of 3D printing: a systematic review.

Diment LE, Thompson MS, Bergmann JHM. BMJ Open. 2017 Dec 21;7(12):e016891. doi: 10.1136/bmjopen-2017-016891.


18. Biomaterials-based 3D cell printing for next-generation therapeutics and diagnostics.

Jang J, Park JY, Gao G, Cho DW. Biomaterials. 2018 Feb;156:88-106. doi: 10.1016/j.biomaterials.2017.11.030.


19. Surface modification of biomaterials and biomedical devices using additive manufacturing.

Bose S, Robertson SF, Bandyopadhyay A. Acta Biomater. 2018 Jan 15;66:6-22. doi: 10.1016/j.actbio.2017.11.003.


20. CT image segmentation methods for bone used in medical additive manufacturing.

van Eijnatten M, van Dijk R, Dobbe J, Streekstra G, Koivisto J, Wolff J.

Med Eng Phys. 2018 Jan;51:6-16. doi: 10.1016/j.medengphy.2017.10.008.


21. The recent development and applications of fluidic channels by 3D printing.

Zhou Y. J Biomed Sci. 2017 Oct 18;24(1):80. doi: 10.1186/s12929-017-0384-2.


22. Bioprinting and its applications in tissue engineering and regenerative medicine.

Aljohani W, Ullah MW, Zhang X, Yang G. Int J Biol Macromol. 2018 Feb;107(Pt A):261-275. doi: 10.1016/j.ijbiomac.2017.08.171.


23. 3D Cell Printed Tissue Analogues: A New Platform for Theranostics.

Choi YJ, Yi HG, Kim SW, Cho DW. Theranostics. 2017 Jul 22;7(12):3118-3137. doi: 10.7150/thno.19396.


24. 3D printed drug delivery devices: perspectives and technical challenges.

Palo M, Holländer J, Suominen J, Yliruusi J, Sandler N. Expert Rev Med Devices. 2017 Sep;14(9):685-696. doi: 10.1080/17434440.2017.1363647.


25. Integrating three-dimensional printing and nanotechnology for musculoskeletal regeneration.

Nowicki M, Castro NJ, Rao R, Plesniak M, Zhang LG. Nanotechnology. 2017 Sep 20;28(38):382001. doi: 10.1088/1361-6528/aa8351.


26. 3D Printing Polymers with Supramolecular Functionality for Biological Applications.

Pekkanen AM, Mondschein RJ, Williams CB, Long TE. Biomacromolecules. 2017 Sep 11;18(9):2669-2687. doi: 10.1021/acs.biomac.7b00671.


27. 3D bioprinting and the current applications in tissue engineering.

Huang Y, Zhang XF, Gao G, Yonezawa T, Cui X. Biotechnol J. 2017 Aug;12(8). doi: 10.1002/biot.201600734.


28. 3D Bioprinting Technology: Scientific Aspects and Ethical Issues.

Patuzzo S, Goracci G, Gasperini L, Ciliberti R. Sci Eng Ethics. 2018 Apr;24(2):335-348. doi: 10.1007/s11948-017-9918-y.


29. Three-dimensional printed upper-limb prostheses lack randomised controlled trials: A systematic review.

Diment LE, Thompson MS, Bergmann JH. Prosthet Orthot Int. 2018 Feb;42(1):7-13. doi: 10.1177/0309364617704803.


30. Bone tissue bioprinting for craniofacial reconstruction.

Datta P, Ozbolat V, Ayan B, Dhawan A, Ozbolat IT. Biotechnol Bioeng. 2017 Nov;114(11):2424-2431. doi: 10.1002/bit.26349.


Sample exam questions:


  1. What are the major technical challenges in applying 3D printing to surgery at present, and what are the promising solution approaches?

  2. What are the major technical challenges in applying artificial intelligence to medical 3D printing at present, and what are the promising solution approaches?